With the predominance of modern technologies, network solutions, and growing importance of Big Data, digitalisation of industry is imperative to keep up with progress. The Slovak Ministry of Economy is taking a multifaceted approach, in order to facilitate digital transformation and application of key innovation technologies, which have great potential for individual companies and whole sectors to decrease expenditures and accelerate growth. Together with new business models and innovative SMEs, this will change the traditional value chains and bring opportunities for new businesses (and startups), as well as those already established.